This is my concern as well because I just had to purchase my second HD500X to get me through a couple of gigs.
The footswitches on my first 500X starting behaving the same way as blitzt29's HD500 (switches sometimes needing more than one press to activate). Then recently during a live show (a couple of shows actually), my patches starting changing by themselves! Mid-song! I cannot verify this but, I think as my switches have worn over time, they have become very susceptible to vibration, whether it be stage vibration or strong bass notes from our bass player. The unit is not even two years old and I'm very gentle with my gear. I've noticed many of the switches no longer "click" when depressed. I am hoping I can order replacements from Line 6 to get my first unit back up and running.
So, all this to say that I really want a Helix but, even though it's built like a tank, if the footswitches are the same as in the HD500X then that worries me.
For what it's worth, I had footswitch problems way back when I had a Vetta and it's footcontroller (I think it was called FB1). Line 6 was gracious enough to send me replacements free of charge.