Finally I have understand what is happening :D . The fx send jack is line level, so it can't go well with an instrument input like my amp input. The only solution is a reamp box to conect "fx send" to "amp input". Line 6 have put a line/instrument selector in the hd500 for this, but in x3 live it ins't possible to change this.
here you can read about it: http://de.line6.com/supportarchive/thread/53173