I run Mixcraft 8 Pro on a PC (Win 10) and have the known issue that when switching presets a few times, Mixcraft crashes. I found that if I have the first setlist that opens in Native be the one I want to work in, AND if I have Native "off" when changing to a diff preset in that setlist, I can't crash it - I tried! Once I change to a diff setlist, it crashes after a very small number of times switching presets even with Native not active. I was skeptical of this, so I've tried it a couple days in a row, and it's consistent for me.