The only software you really need is Line 6 Edit. This is for editing and storing you tones. That's all you can really use anyway. Just make sure to read fully on installing (Java can be an issue sometimes) and also make sure you have a decent MIDI interface. If you have no MIDI interface then Line 6 recommend the MIDISport Uno as a relatively cheap but robust interface - it is MIDI to USB so can be connected directly to your computer.

A good general Pod2.0 FAQ for you :

http://line6.com/support/docs/DOC-4728

Connecting to a computer:

http://line6.com/support/docs/DOC-4725

Line 6 Edit can be downloaded here:

http://line6.com/software/