i've listened to the clip and a couple things stand out to me.  It sounds like there's more than one guitar, or the bass is quite distorted.  Listen to the intro/bridge.  He's got what sounds like whammy AND wah going on in the lead line while the fuzzy rhythm tone is playing underneath.

For the lead tone, I would use the whammy as jim demonstrates below, but use 50% min and 75% max on the exp pedal.  So you go from unison to +1 octave.  I would also put a wah pedal in the chain and set that to 0% min and 100% max using the same EXP controller.  IE - assign them both to EXP-1 or EXP-2.  The mix on the pitch glide should be 100%.

The main rhythm tone during sounds like a heavy fuzz distortion with a -1 octave in front of it, mix at 50%.  There's a few things to try out.  I'd start with the sub-octave fuzz distortion.  That might be all you need.  Otherwise, I'd try a pitch glide set to -12 with mix at 50% and not have it controlled by the exp pedal into a fuzz distortion or Overdrive distortion.  If it's not fuzzy enough, try boosting bass in front the fuzz via an EQ effect.

What is it that does not sound right?