Hey reggev,

  Make sure that you have the most recent version of the Line 6 drivers and Monkey installed as well:

  Windows Drivers 4.2.4.9:

  http://line6.com/software/readeula.html?rid=4143

  Line 6 Monkey 1.43:

  http://line6.com/getrelease?rid=4223

  After successfully installing Line 6 Monkey and the drivers please try removing any additional unnecessary USB and firmware devices from your computer when troubleshooting this issue. Make sure to connect it directly to a USB port and not a USB hub, extension, or keyboard of any kind, preferably connect it to a USB port on the rear of computer. Try using additional USB cables and every USB port available.

  Launch Line 6 Monkey and apply any updates that are available. 

  To ensure your Windows Vista or 7 computer is optimized to work with audio processing, please follow the link below for a official Microsoft optimization guide that has some more suggestions other than the ones provided in the our optimization videos.

http://windows.microsoft.com/en-US/windows7/Optimize-Windows-7-for-better-performance

  I would also suggest that make sure that UX1 is set up as your computers sound card, to do so reference the video tutorial at the link below:

  http://line6.com/support/docs/DOC-2083

In addition, if you are using a DAW, try increasing the buffer size on the audio preferences menu. As well as changing the buffer size on the Line 6 Audio-MIDI device menu which is located on the Control Panel. This will increase latency, so you will have to experiment which setting works best for your computer.

Hi, there is solution.

1. Go to your system settings (Start -> Controll panels)
2. Open "Line 6 Audio-MIDI Devices"
3. Set buffer size to higher values (increases lattency little bit but removes CPU usage and cracks from output).
4. Hit Apply and enjoy.

Works fine for Windows 7.