FWIW, Line6 did officially post an announcement (at the top of the forum).

Announcement: Mac OS X 10.8 Mountain Lion Audio Problems

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Hello Line 6'ers,

Line 6 is aware of the current issues with our drivers and OS X Mountain Lion.  We are diligently working on a release that addresses the audio artifacts and expect to have a release in the next couple of weeks, barring any unforeseen issues.  Please continue to watch here for further updates.

Best regards,

Line 6 Support

Line 6 just released an updated driver. According to my tests, it corrects the issue about the noise during playback or audio recording on Mac OS 10.8. But I now have an important latency, even with the lowest settings. It's strange... Looks like a second update will be necessary.

Could anyone check and tell me what he/she gets ?

Thanks.

Nothing is fixed for me...

Cannot even listen to a mp3 in iTunes... every time I try to do something else, the sound cracks, bumps, stops... (anything... emptying trash, switching desks, exposé (well Mission Control now), typing an email...)...

Very very very disapointed.

The New driver does not work for me, still have the crackling via USB. I don't even think the new driver is installing properly. If my HD500 is not connected, line 6 monkey says the new driver is not installed and needs to be, even though i have installed it like 3 times now. After installing the new driver, if you hold a few seconds before pushing restart, two error msgs come up stating problems with intstalling. Anyone else having issues with the new driver???

With MacOS 10.8.2 the latency is fine again but the noise/crackling came back...

Simply a shame. Line 6 seems to be an unprofessional company. I'm definitely disappointed.

OK.. The new driver was released and it didn't fix my problems.

The cracking/poping noise was still appearing during the recordings. It was a big noise and then it cracked for 10 seconds and then stopped. Then it haeppened again and again. I opened a ticket suport for this which is still opened without resolution.

This week my Toneport UX1 gave a new trick: when I connect it to my macbook it goes green for a minute, but the sound of the instrument/mic is zero. Also my USB mouse goes away.

After a minute or two, the light simply goes red and the line 6 device is no longer recognized by the Mac OS X. When I go to Line6 Audio Devices on System Preferences it says "no line 6 product connected".

Please, am I the only one? I'm getting preety tired with this story. This time I'm thinking really serious about buying another product. Can't record anything since Mac 10.8.2 came out.

They seem to have fixed it temporarily with 10.8.1 but it's all f*#ked up again with Mountain Lion 10.8.2  They'll probably have it fixed in another 6 months to a year. They'll spend the first few months denying there's a problem, ignoring the service tickets, and then trying to blame the trouble on someone or something else. Thanks for nothing, Line 6.