if i understood right, if there's no amp chosen in the Pod, the DT will use his standard preamp model wich depends on the selected voicing?
So a preset basing on "no amp selected" will sound different, depending on your former preselection on the DT.
Independent from the preamp model and the poweramp section, it will always be hard to get a ccoustic sound from an amp made for electric guitar as the speaker in such an amp is not made for neutral reproduction but für sound forming.
i made a quick and dirty measurement of the line6 celestion G12H90 from my DT25 Combo:
So there's a lot of midrange and just few bass and treble but both are needed für acoustic sounds more then für electric sounds. Other guitar speakers have a similar behaviour.
I found some pretty good acoustic sounds in the customtone database and they all base on the utilisation of lots of EQing to eliminate the guitar speakers character. And with a lot of WQing, there often come a lot of unwanted noise.
For the moment i feel therefore more comfotable to play my HD500 in a linear bass amp with tweeter (homemade combo with a markbass amp, a faital 15 FH500 and a Faital HF500 with tactrix horn ST500. Fore some sounds, HD+DT sounds still better to my ears, especially with a powersoak, but with a neutral amplification i'm more flexible and get easier the same sounds live and when recording ;)
In fact, for some things i'm to stupid for the line6 link (even if it's basically a great idea), so if i have a similar (linear) environment for both livesound and recording, the world is a bit more easy for me.