Hello, sorry for my poor English, it's not my native language.
I have Core2Duo, 4GB RAM, Windows 8 x64, latest drivers, no USB hubs etc... and Core i5, 8GB RAM, Windows 8, x64 (notebook) and both have the same problem.
USB link hangs periodically, sound stops, media players freezing (but ASIO driver still works!). If i replug the cable, windows device manager detect hd500 but device state is "The drivers for this device are not installed", only restart helps. It happens only when i use Google Chrome (or any other browser) and watching online video. This problem is not observed with other audio interfaces or built-in audio. I tried earlier versions of Adobe Flash and Line6 Drivers - this does not work. Problem can be solved only by removing Adobe Flash Player and disabling built-in player in Chrome, but it is not a good solution.
UPD: the problem has returned. Still no sound loss in video games and other software (ASIO driver works fine even after Windows Audio hangs), but in the web browsers it is still there, when playing online video or audio (now in HTML5 mode).