Hi, I've also had this problem trying to update Monkey on Yosemite. It won't let me run pod farm and says license isn't found. When I open license manager it says I am licensed. I've tried deleting and moving the audio drivers in the manner suggested by previous posts and it did not solve anything. It's been more than a month now since I have been unable to use my ux2 with pod farm. Whether the problem lies with Apple's updates or not, there must be some sort of basic fix that line 6 can put forward as I don't plan on waiting to see if Apple's next update doesn't have this problem to use recording software, and will buy something from another company if no solution is offered.
Thanks!