I understand, but e.g. Avid Eleven Rack have seperate outputs for amp, like balanced/unbalanced in POD and you can set up which processing is applied for this outputs.
It can be acceptable, but this thing which I mentioned, that I cannot enable cab simulator for external preamp disqualifies POD for using with external tube preamp... unfortunettly because I would more than love to use POD with my tube preamp and tube power amp... but I don't want to lose possibility to use tube preamp when I'll play witout cabinet.