The difference in the variax 22 fret neck and say a tele 22 fret is the 22nd fret on a tele neck over hangs the heel of the neck where the variax’s 22nd fret does not. So I would say a 22 fret tele neck would work if you used a spacer at the neck heal joint the same size as the overhang on the tele neck. Probably would have to fill and redrill the neck mounting holes . Could be done and if done right you probably wouldn’t be able to tell it . The fingerboard overhang would cover up the spacer.