I think most of that functionality exists using templates and set lists.
https://manuals.line6.com/en/helix-stadium/live/presets
I have my standard Fender Twin template, load a new preset based on that template, make the appropriate tweaks for the specific song, then save that song.
Once that is done, create a setlist under user presets and drag and drop the songs into the setlist.
Depending on your global settings, if you make settings on the fly and save them, that songs settings will change on all saved set lists and the parent.
if you don't want to save, just bank to a different preset and it will go back to the original version.