I have An Apple MacBook Pro i7, running El Captain 10.11.6. I recently upgraded to El Captain and did not have any issues using GearBox with Yosemite.
If I launch GearBox without my TonePort UX2 plugged into the USB, GearBox will start up just fine but when I plug the USB in for my UX2 I get the pinwheel of death.
If I launch GearBox and have my UX2 plugged in before i launch, it gets stuck on "Initializing DSP"
I downloaded POD Farm 2 and it woks but only in a trial capacity as I have not purchased the program, but it does works with Garageband.
I can launch Garage Band and use my TonePort and the effects Garage Band has pre installed.
All my drivers are up to date according to Monkey.
It all seems to revolve around GearBox.
Any known solutions to this?