This is a related, but not exactly same question: Can we get an option for "global cab off" only for certain channels, for example, on 1/4'' outputs?
I have a Kemper, which has this option where you can do global cab-sim off only for monitor out (which is mono). This allows users to use a power amp/guitar cab as their monitor and send the cab-simulated XLR output to FOH. I know you can do this on Helix, using parallel routing etc. But this will eat up DSP power and routing possibility and moreover, will have to be done per-preset, which is not ideal...
I think Helix's tone comes quite close to Kemper in terms of dynamics and usability, but with two issues I see including this (another one being patch switching gap), I might have to return this great device.
-Jake