From a "non-experimental" perspective. if you are using a Noise Gate you are making something in your chain do something that it does not do well. If you want to limit sound from your gat while you are not playing it, use a Hard Gate. But any pedal or effect that is used to take away things from your sound is simply a bad thing. EQs and the like excluded of course which is another topic. Figure out what is creating that sound and replace it with something that actually works.
From an experimental perspective, if you are adding something into your chain to filter your sound because it achieves some special tone, then go for it. Most guitarists will find a way to achieve the sound they desire without a bunch of wizardry. That's where the balance between new technology, gear knowledge, and playing ability must be achieved. That said, I have never been one to shy away from an experiment.
As a minimalist, I am fascinated by the challenge of achieving a sound with as few robots as possible. There are a lot of ways to skin a cat... I like cats. Be nice to your kitty.