I have a HX-Stomp. and a Marshall 9005 50 watt stereo tube power amplifier.
Because this is designed to take a Marshall Tube rack Pre-amp it will add power amp flavors to your sound, so i run just the pre-amp section of amplifiers.
In My experience Marshall Style sounds work flawlessley and sound even better. But Mesa /Fender sounds lose some of their magic. still very usable but a Dual Rec doesn't have the Bass and Fenders lack high end Sparkle. But you can get an amazing Peavey 6534/ EVH 5150 El34 Sound using the Panama pre-amp.
So It depends on what your are trying to achieve