I'm gonna post my full system specs for you:
-Windows 10 Pro with 1903 May Update
-MSI Z370 M5 Gaming
-i5 8600K
-Palit GTX 1080
-4x8GB samsung m378a1k43cb2-crc (overclocked to 3200 MHz)
-system drive: Samsung 840 series 250GB
-sound card: Yamaha AG06
any further specs you need? I already did: Windows repair/upgrade installation, deleting, (re-,de-)installing Helix, de- and reactivated .NET Framwork 3.5 and 4.7, de- and reinstalled sound and graphics drivers, restarting in safe mode, adding another user account/activating administrator account, deleting all line6 files from the pc.
I simply can overwrite 1.81/2.81 with the 1.70/2.70 and both (native and hx edit) start immediately.