Last night I was checking out the Stereo capabilities of the HX One and ran into an issue. I was on some Reverb effect, I can't remember which one, and Held down the Effect knob to select a Delay. It switched over to the delay, and it no longer output any sound out of the pedal. In addition the top 3 rotary knobs stopped working. I could select other effects, saved patches, access the tuner (and tune) but still no Sound out. I had to cycle power to resolve the issue.
The locked up rotary knobs are similar to the same-effect-loading-midi-issue described in the other thread.
I have no hopes on anybody from Line 6 to actually fix this issue based on previous lack of response on issues related to HX One, but I wanted to describe the issue to the community. I gather support of HX One is even less now that they released a bunch of new flagship products. It's a great pedal with a good interface when it works.
Maybe others have had similar problems to this?