Hi,
I've just resurrected my HD 500 for church worship.
After downloading from the Line 6 website, I'm currently running "Line 6 Monkey", version 1.77 and "POD HD500 Edit" version 2.27 on Windows 11.
I also have a POD XT Live for which I've downloaded and will use "Gearbox" to edit patches on my PC.
My desktop PC is a new MSI and came with Windows 11 installed on it.
I've not seen any pop up complaining about "Memory Integrity".
However when running Monkey it states I need new drivers (from version 4.2.7.6 to version 4.2.7.7).
But in another topic, Support has stated that driver version 4.2.7.7 is causing an issue and that we should install and use version 4.2.7.6... which I am, with no issues.
Hope this helps.