The easy solution is to learn sound engineering. You don't need to know all the ins and outs, but knowing some of the basics will help you dial in a patch a lot quicker. With a modeler, you are no longer a guitarist plugged into an amp that's in the room. You're basically dealing with a miced amp in a studio. Knowing how to use EQ and compression, along with proper gain staging, will help reduce your tinkering time.