Pick one amp model. Just one. One you are already familiar with in the real world. Use an amp + cab block to keep things as simple as possible. Start with the default cab that in the amp/cab block. Tweak the mic or cab if you want along with the main settings on the amp - drive and amp EQ. Get your tone right with just that and skip everything else. Don't keep switching amps, cabs etc. but instead learn one model and cab. Once that's good, introduce delay and reverb and then maybe a dist block. The longer you can keep things simple the more comfortable you'll be with getting things to sound good and consistent.
That's a good place to start. After you're good with that then expand to more effects, more amps, advanced routing etc.
I would NOT start with watching other people's videos. The guitar they are using is different, How they play is going to be different. Probably the amp model they are going to use is not the one you are most familiar with. Don't start with the presets either. Start with a blank patch, one amp/cab block and keep things as simple as possible. No way to get overwhelmed that way.