I have a HP Windows 8 system, UX 2 and Reaper always works, but the media players sound disappears!! only "restarts" seemed to make the media players work again.
I uninstalled drivers, and just now tried to disable the USB setting as mentioned above and hopefully this is the fix.
I tried numerous Media players all had the same issue.
On my system the songs, MP3 would play and the everything seemed fine except the UX 2 was silent. Then I checked the recording side and everytime this worked well....It is NOT the UX2 or Reaper DAW.
This is a Windows 8 issue. 64 or 32 I dont know. Its a major pain in the ask... Sometimes the audio plays for 20seconds sometimes for a hour or so.
I left the pc sitting for 10hrs and it didn't work when I came back and tried to play a MP3. (The internet was turned off the entire time. So its NOT the internet either and Not a Update issue)
This seems to be a power setting issue and most likely USB port related, driver or sleep setting? I don't know.
I put the USB power setting to High Performance and USB setting to DISABLE, as mentioned above.
The good news is the Reaper and UX2 always work fine and all my MP3 can be played back in Reaper! No problem.
This also makes me think the ASIO works and the media players /USB is the issue via Windows 8.
My daughter hates Windows 8 so much she bought a Apple for the first time. If Microsoft trys charging me to fix their problems ....I'll be buying a MacBook too.