I have been adjusting the "db" value of the IR and/or the Level value of the snapshot at the output block. I had struggled with volume/gain levels and volume matching between presets in my previous experiences with the Helix, but I am now trying to make my presets "more or less" level in volume to an empty patch. That means that for gainy amped signal chain for driven electric guitar sounds, I am turning down the channel volume so that it is close to the empty preset level. That makes it a lot easier to have balance with an acoustic signal chain without an amp. I am still experimenting with this setup and haven't used any of this live yet (like where am I going to play right now anyway, right?...).
I am going to start building presets with 2 separate signal chains, 1 for cranked electric guitar and 1 for acoustic sounds and I hope to get them both in the same neighborhood volume wise. I am going to use a guitar with 2 separate outputs, 1 regular mags, and 1 piezo with these presets.