My experience with PC212 and PC112+ is perhaps a little different. I had both for a couple of year now, and use one or the other depending on venue size and stage footprint restrictions. I have found PC212 to have excess low end when set on the floor compared to the PC112+, that's likely because there's must more bass coupling with the floor with 2x12 than 1x12.
I've also struggled with stage volume with the PC212. It seem harder to find the sweet spot, its either missing in the mix or way too loud. I don't seem to have that issue with PC112+, probably because the PC212 might just be too big compared to the rest of the band.
I use FRFR mode only, and use IRs in Helix or cab models in Quad Cortex. I found that comparing the PC112+ and PC212 with a real amp, with an IR in Quad Cortex that matches the G12-65s in the amp, the PC112+ sounded closer to the real thing than the PC212. The PC212 had a different midrange color that didn't match up as well to me. The PC112+ and PC212 do use different Eminence speakers, so that could account for the difference.
Overall I think I prefer the PC112+: it's smaller, lighter, likely fits with the rest of the band better, doesn't over-extend the bass as much, and seems to have a slightly more pleasant overall tone to me. I do like the PC212 stereo, but as a practical matter, its lost in the mix. And I use IEMs anyway so I get the stereo in my ears anyway.