I echo the thoughts above for DT amp users.
I can have global EQ if I use 1/4" out, but then I lose the ability to change the power amp settings with my Helix because I'm not using AES/EBU.
Or, I can have the really cool DT power amp switching from my Helix, but then I lose the global EQ.
So I have to choose which features I don't want to use which is a pain because I would like both of them.
The only solution I can see is three duplicate set lists. One for 1/4" out (and I'll just have to remember to fiddle with the amp between songs), or L6 Link out with a 'neutral' EQ for each preset. One for L6 Link out with a 'brighter' EQ in each preset, and one for L6 Link out with a 'darker' EQ in each preset.
It's either that or have two eqs in every patch to go 'bright' or 'dark' based on the room we're playing in.
Neither of the above lets me tune the amp to the room at sound check.
I have voted for all I can to do with this on Ideascale.