I use the Global EQ when I'm tweaking or coming up with new patches at home. My current speakers are not FRFR and I compensate for that, and the boominess of my living room, via the Global EQ. I've compared enough how the patches sound in my living room and in most live situations so I have a general idea which frequencies to boost or cut. For live gigs, Global EQ would be off. I leave the fine equalization of the venue to the sound guy, Im fortunate enough to have one every gig.