I have a Helix Floor and I control which patches I use on my ToneX pedal with the midi out of the Helix. So yes it is possible. The Tonex Lists its midi control in its manual. You go into the Helix control to setup the midi messages that you want a button to control. I have, on some patches, for fs 1 to bank up on the Tonex and fw 5 to bank down.
You can control other things but that is what I use it for. You have to use the 5 pin midi though, the usb from a Helix would not work.