I'm fairly new to tone building here too, but so far my go to amps have been Vox AC 30 (Essex A 30), Matchless DC 30 (Matchstick Ch 1), and PRS Archon (Archetype Clean). I was thinking I should explore some of the other amps - and this thread has given me some pointers on where to start, so thanks!
Useful resourse linking real life names to Helix names is at https://helixhelp.com/models.
One thing I learned already - check out the cab options, and the mic options on the cab. They can have a huge impact on the sound before you even touch the amp controls.
+1 on Jason Sadites you tube channel - an enormous amount of great information and pointers there!