Obviously the good news is that your Helix is fine.
the bad news is that your issue is almost certainly driver conflicts, and these are notoriously difficult to resolve, because there is no solution that fits all problems.
If it were me, I would start with expunging everything Line 6 related from your PC. This means uninstalling all Line 6 software and making sure that no Line 6 drivers remain - once you've removed all the Line 6 software, plug your Helix in and check your device manager. If you find your PC is detecting the Helix and still loading drivers that aren't class-compliant default drivers, uninstall these drivers too.
Then reboot, and reinstall the latest version of HX Edit *only* as this should contain all the necessary drivers and the Line 6 updater, and see if this resolves your issue.
Apologies if you've tried all this, but unless you state what you have tried there's no way of knowing.