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When does the noise happen - when recording? Is the noise recorded? Does it happen on playback? Usually something like this can be eliminated by adjusting the buffer setting in the DAW.

Any plug-in (not just Pod Farm) latency is going to be dependent on your interface/DAW buffer settings. What is your actual latency? (not familiar with Studio One, Reaper shows it in the top corner). RAM and hard drive don't really affect latency numbers, its your processor speed that is the biggest factor. Make sure you have other things shut down while recording (wireless, internet, etc), this may allow you to lower the buffer more.

No, that is not possible. You would need to use the FBV Shortboard for that. The work-around is to set up your presets in any bank of 4 to do that, for example, 'A' doesn't have distortion or chorus, 'B' has distortion, 'C' has chorus, D has both distortion and chorus.

Please describe exactly what you are doing and listening to. Headphones in mono - meaning you only hear sound from one earphone, or that the same thing is coming out of both? Do you have the headphones plugged in with any kind of adapter? If it is sound from just one earphone, then your PodFarm (or other audio settings) are set to mono.

Without listening to your video, the symptoms sound like a compressor that has kicked on full.

I run PodFarm2 on a (PC) 64 bit machine in 64 bit Reaper.... maybe Macs are not so friendly for this? The Helix is quite a useful tool for those playing live (electric) guitar. I know people who have ditched their amp set ups, using a Helix to plug into the main PA system. Of course this depends on your band's set-up, too. For me, what is missing from a pure 'plugged in' stand point (i.e. no actual guitar amp) is the 'feedback' (not squeals!) that comes from the guitar body and pickups receiving the amplified sound from the speaker. My personal preference is always to mic the amp (but I will often record a dry DIed track at he same time). The one difference I do is when recording a 12 string electric - I've found the right combination of guitar tones in PF2 that really brings out the 12 string sound.

The advantage of using 'plug ins' when recording guitar, rather than external hardware, is that you can record a dry signal, listen to a processed signal - and record/change the processed signal at any point, I'm not familiar with the Helix floor unit, but it would need to send both dry and processed signals to the DAW to do what you want. I'd recommend going with a software option. Any audio interface that accepts instrument input will work for you. Any DAW (recording software) will work for you too. The only real difference between different DAWs is work flow and user interface.

When I changed from Gearbox to Podfarm, the user patches did not transfer as they use a different format. Note, also, that the free version cannot be used as VST, only as stand-alone. You can use Podfarm when recording by setting the input of your DAW to Podfarm, of course, but not as in insert on a track, so that means you cannot change any settings after recording, the way you can with a VST.

I agree with Phil - Bluetooth latency (delay) would make it very hard to use. I had some wireless (non Bluetooth) headphones that had the same problem, the delay was not as bad as Bluetooth can be, but it was enough to make it a problem.

You do not want to run it in mono with only one speaker cable hooked to it, this will cause an imbalance in the amplifier section and eventually cause something to burn out. If you run two cables to one set of speakers (hooked up in mono), it will change the impedance the amp sees. Make sure you are using speaker cables and not instrument cables (which are not suitable for the voltage/power).

Not familiar with FL, but it sounds like you need to change the buffer settings.

Sounds like the adapter is at fault for the headphones. Get a different one. Voiceover work, typically you would want to use EQ (to match your voice and the recording space) and some compression.

Ok, KBX, whatever. You show one picture of a corner set up, then 'say' you have all this other stuff. Velvet curtains and foam do not absorb bass - unless you've got about 24" thick foam, that is. They will absorb high and mid-high frequencies, which is what most people hear as problems. The low end 'mud' won't be noticeable until you listen back on a system that reproduces them correctly. I am talking about monitoring (listening) to the music/mix - all this is far less important than when tracking via mic. Corners are notorious for bouncing around low frequencies - even that 'corner' where the bureau is on the right side of your desk will bounce around sound. Hearing bass and kick on those monitors? No, you are hearing the harmonics of the low frequencies, not the actual low frequencies - it's physics, you can't argue with science. Look at the frequency curves for the speakers, they can't reproduce the low notes.

Looks like Line 6 removed the list they had posted on this site (probably when Spider V came out). But here's one for you: http://www.musifex.pt/media/itemfiles/SPIDER_IV_15/pdfs/Misc_-_Spider IV Song presets .pdf

Do you have your computer connected via the USB-B port? (That's the squarish one). Assuming you do, turn on the computer first, then plug in the USB connector, then boot up Cubase. The amp should come up as an audio input option. If not, try a different USB port on your computer. If you already have another USB audio device connected, your computer might not recognize a second one plugged in at the same time.