I'm confused by your choice of words, whats a gizmo? Are you asking if you can use the Helix into your power amp section then yes. You can. However that seems to be the least preferred method of powering a helix. This will give you the option to use any head tone into the power amp section so you can get a wide variety of tones.
I've personally tried this with a Blackstar series one. it worked alright, but doesn't quite offer the same ease of use with FRFR speakers or even a power amp to a guitar cab. My personal preference is the Helix into a power amp out to a 2x12 cab, while also running out to 2x12" frfr speakers. Pushes air like a 4x12, but gives a mix of tone and sounds huge.