For my needs, factory presets are useless. There was a factory setlist that went through the amps, which i spent about 2 days going through and deleting out the effects (or just bypassing them) and leaving the amp/cab. If they were separate blocks or the single block I dont remember. However, i literally went through all the amps in the Helix and dialed them in to various gain stages, found out what I liked that amp to do best, and saved it as a user default (not a favorite). Yes tedious, however, if you utilize the looper trick (if you dont know that one, its where you put a looper at the beginning of your chain, record your guitar and then that allows you to tweak the amp/cab without having to stop playing to adjust. the Looper is like a friend playing for you) and it didnt take long to dial in the amp variously.
For your case, here is what I would do. And remember get your tools in order and it's much easier to build a house.
1) create a template. For your purpose, I would create a blank preset. Set up your typical preset flow. For me, line 1 input is guitar, line 1 output is set to line 2, line 2 output is set to -4db and multi as the output option. I would add the looper block first in the chain, and assign the bypass parameter to a footswitch. I would add an Amp +Cab Block at the end of line 1 (or first block on line 2). This allows you to add pre/post effects easily DSP wise. Save this as Template or something easy.
2) record your typical playing style into the looper with the amp/cab block(s) bypassed so you just hear the straight through guitar. I usually try to cover a variety of play styles when doing this. I'll pick some clean-ish type stuff, bang some chords, palm mute some chords as well as play a few bluesy/rock type lead passes. This lets me hear the most without having to re-record different things.
3) while the looper is repeating this back to you, activate your amp/cab blocks (if separate, do your cab block first so you dont get the raw amp sound, harsh and just ugly). You can literally start at the first amp in the helix, tweak just the usual amp settings (gain, bass, mids, treble, presence). However try to keep volumes even so adjusting the master volume (affects tone) and channel volume (does NOT affect tone will need to work cooperatively to do this. Do it now, so that your user defaults are relatively balanced, or you'll need to do this later when you create presets. remember what I said earlier about organizing tools early?
4) when you get a tone you like, there are two approaches. If you want a one-trick pony tone for each amp.....save it as a user default. Next time you call up that amp, you got YOUR tone. If you want to use an amp to do multiple tones (Deluxe, AC30 type stuff) then I'd suggest saving the block as a user favorite, you can name it as something like Deluxe Clean, Deluxe Pushed, Deluxed Ballz, lol. Again, next time you build a preset, select blocks from the favorites folder and you have YOUR tone.
Those 4 steps can be overwhelming in volume, but really they are foundationally what you need to build upon further. You can do the same thing with effects and such as well. I do that with all my effects. Being in a cover band with over 100 songs available. I create a preset per song, i use my user favorites that i've saved. if I save it as a different setting, i save it as a different user favorite.
Hope that helps!