Variax requires a slightly different approach to a 'real' guitar but it can sound totally awesome with little effort with the Helix. (I have a 59P)
It's a magic combo in my probably easily pooh-pooh-able opinion but I do A>B comparisons against 'real' guitars into whatever valve amp or sound I am trying to get and it never falls short.
It is worth while remembering that not every strat sounds the same, not every....OK you get the point here.